藥物交互作用
Disopyramide + Nilotinib
嚴重程度: 禁忌併用
Disopyramide and Nilotinib: contraindicated interaction.
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摘要
Both agents prolong the QT interval, and concurrent use increases the risk of torsades de pointes and sudden death. Disopyramide also has proarrhythmic potential in its own right.
用白話說明這項交互作用的意義
Disopyramide and Nilotinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Disopyramide belongs to Cardiovascular; Nilotinib belongs to Oncology.
為什麼會發生
Additive prolongation of cardiac repolarization (QT interval).
處置方式
Avoid concurrent use and choose a non-QT-prolonging antiarrhythmic. Correct electrolytes and monitor ECG if no alternative exists.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Nilotinib 的其他交互作用
Disopyramide 的其他交互作用
常見問題
Can I take Disopyramide with Nilotinib?
MediHelp rates the interaction as contraindicated. Disopyramide and Nilotinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents prolong the QT interval, and concurrent use increases the risk of torsades de pointes and sudden death. Disopyramide also has proarrhythmic potential in its own right.
How serious is the interaction between Disopyramide and Nilotinib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and choose a non-QT-prolonging antiarrhythmic. Correct electrolytes and monitor ECG if no alternative exists.
What other medicines interact with Nilotinib?
MediHelp also lists interactions of Nilotinib with, for example, Amiodarone, Arsenic trioxide, Dofetilide. The full list is on the Nilotinib page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
