藥物交互作用
Doxycycline + Strontium ranelate
嚴重程度: 中度
Doxycycline and Strontium ranelate: moderate interaction.
最後更新
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摘要
Strontium ranelate can chelate with divalent and trivalent cations and form complexes with doxycycline, reducing doxycycline absorption. Antibacterial levels may be subtherapeutic.
用白話說明這項交互作用的意義
Doxycycline and Strontium ranelate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Doxycycline belongs to Anti Bacterial; Strontium ranelate belongs to Musculoskeletal.
為什麼會發生
Chelation reduces doxycycline absorption
處置方式
Separate dosing by at least 2-3 hours, or suspend strontium during the doxycycline course.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Doxycycline 的其他交互作用
Strontium ranelate 的其他交互作用
常見問題
Can I take Doxycycline with Strontium ranelate?
MediHelp rates the interaction as moderate. Doxycycline and Strontium ranelate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Strontium ranelate can chelate with divalent and trivalent cations and form complexes with doxycycline, reducing doxycycline absorption. Antibacterial levels may be subtherapeutic.
How serious is the interaction between Doxycycline and Strontium ranelate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate dosing by at least 2-3 hours, or suspend strontium during the doxycycline course.
What other medicines interact with Doxycycline?
MediHelp also lists interactions of Doxycycline with, for example, Acitretin, Aminolevulinic acid, Cholera vaccine. The full list is on the Doxycycline page.
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