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藥物交互作用

Gemifloxacin + Strontium ranelate

嚴重程度: 中度

Gemifloxacin and Strontium ranelate: moderate interaction.

最後更新

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Strontium ranelate chelates divalent cations and binds gemifloxacin in the gut, reducing gemifloxacin absorption. Lower antibiotic levels may cause treatment failure.

用白話說明這項交互作用的意義

Gemifloxacin and Strontium ranelate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Gemifloxacin belongs to Anti Bacterial; Strontium ranelate belongs to Musculoskeletal.

證據等級: Moderate

為什麼會發生

Chelation reduces oral gemifloxacin absorption

處置方式

Suspend strontium ranelate during the short gemifloxacin course, or separate doses (gemifloxacin at least 3 hours before or 2 hours after).

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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建立帳號並開始 Pro+ 試用,即可解鎖 Gemifloxacin 與 Strontium ranelate 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Gemifloxacin with Strontium ranelate?

MediHelp rates the interaction as moderate. Gemifloxacin and Strontium ranelate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Strontium ranelate chelates divalent cations and binds gemifloxacin in the gut, reducing gemifloxacin absorption. Lower antibiotic levels may cause treatment failure.

How serious is the interaction between Gemifloxacin and Strontium ranelate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Suspend strontium ranelate during the short gemifloxacin course, or separate doses (gemifloxacin at least 3 hours before or 2 hours after).

What other medicines interact with Gemifloxacin?

MediHelp also lists interactions of Gemifloxacin with, for example, Arsenic trioxide, Dofetilide, Ibutilide. The full list is on the Gemifloxacin page.

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