藥物交互作用
Dronedarone + Hydroxychloroquine
嚴重程度: 禁忌併用
Dronedarone and Hydroxychloroquine: contraindicated interaction.
最後更新
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摘要
Dronedarone prolongs the QT interval and hydroxychloroquine adds to this effect, increasing the risk of torsades de pointes. Dronedarone's labeling advises against combination with QT-prolonging drugs.
用白話說明這項交互作用的意義
Dronedarone and Hydroxychloroquine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dronedarone belongs to Cardiovascular; Hydroxychloroquine belongs to Musculoskeletal.
為什麼會發生
Additive delayed ventricular repolarization through potassium channel blockade.
處置方式
Do not combine; choose an alternative antiarrhythmic or an alternative to hydroxychloroquine.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Hydroxychloroquine 的其他交互作用
Dronedarone 的其他交互作用
常見問題
Can I take Dronedarone with Hydroxychloroquine?
MediHelp rates the interaction as contraindicated. Dronedarone and Hydroxychloroquine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Dronedarone prolongs the QT interval and hydroxychloroquine adds to this effect, increasing the risk of torsades de pointes. Dronedarone's labeling advises against combination with QT-prolonging drugs.
How serious is the interaction between Dronedarone and Hydroxychloroquine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; choose an alternative antiarrhythmic or an alternative to hydroxychloroquine.
What other medicines interact with Hydroxychloroquine?
MediHelp also lists interactions of Hydroxychloroquine with, for example, Arsenic trioxide, Cisapride, Pimozide. The full list is on the Hydroxychloroquine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
