藥物交互作用
Chlorpropamide + Dulaglutide
嚴重程度: 中度
Chlorpropamide and Dulaglutide: moderate interaction.
最後更新
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摘要
Dulaglutide increases glucose-dependent insulin secretion, and with a sulfonylurea it raises the risk of hypoglycemia. Chlorpropamide's long half-life can prolong any episodes.
用白話說明這項交互作用的意義
Chlorpropamide and Dulaglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chlorpropamide belongs to Endocrine; Dulaglutide belongs to Endocrine.
為什麼會發生
Additive insulinotropic effects of GLP-1 receptor agonism and sulfonylurea-mediated insulin release.
處置方式
Consider lowering the chlorpropamide dose when dulaglutide is started and monitor blood glucose.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Chlorpropamide 的其他交互作用
Dulaglutide 的其他交互作用
常見問題
Can I take Chlorpropamide with Dulaglutide?
MediHelp rates the interaction as moderate. Chlorpropamide and Dulaglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dulaglutide increases glucose-dependent insulin secretion, and with a sulfonylurea it raises the risk of hypoglycemia. Chlorpropamide's long half-life can prolong any episodes.
How serious is the interaction between Chlorpropamide and Dulaglutide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider lowering the chlorpropamide dose when dulaglutide is started and monitor blood glucose.
What other medicines interact with Chlorpropamide?
MediHelp also lists interactions of Chlorpropamide with, for example, Ethanol, Exenatide, Insulin degludec-insulin aspart. The full list is on the Chlorpropamide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
