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Drug interactions

Elivaldogene autotemcel + Human papillomavirus vaccine

Severity: Moderate

Elivaldogene autotemcel and Human papillomavirus vaccine: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Vaccine safety and efficacy during or after elivaldogene autotemcel have not been studied. Myeloablative conditioning and subsequent immune reconstitution are expected to impair vaccine responses.

What this interaction means in plain words

Elivaldogene autotemcel and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Myeloablative conditioning and hematopoietic reconstitution impair vaccine responses.

What to do

Vaccinate at least 6 weeks before myeloablative conditioning where feasible. Defer vaccination until hematologic recovery, then revaccinate per guidelines.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Elivaldogene autotemcel with Human papillomavirus vaccine?

MediHelp rates the interaction as moderate. Elivaldogene autotemcel and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vaccine safety and efficacy during or after elivaldogene autotemcel have not been studied. Myeloablative conditioning and subsequent immune reconstitution are expected to impair vaccine responses.

How serious is the interaction between Elivaldogene autotemcel and Human papillomavirus vaccine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate at least 6 weeks before myeloablative conditioning where feasible. Defer vaccination until hematologic recovery, then revaccinate per guidelines.

What other medicines interact with Human papillomavirus vaccine?

MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.

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