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藥物交互作用

Elvitegravir / cobicistat / emtricitabine / tenofovir df + Raltegravir

嚴重程度: 禁忌併用

Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir: contraindicated interaction.

最後更新

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

The elvitegravir-containing product is a complete single-tablet regimen, and adding raltegravir duplicates integrase inhibitor therapy with no established benefit. Safety and efficacy of this combination have not been studied.

用白話說明這項交互作用的意義

Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

證據等級: Low

為什麼會發生

Therapeutic duplication of two integrase strand transfer inhibitors; no established pharmacokinetic mechanism.

處置方式

Do not combine; use the complete regimen alone or build a regimen with raltegravir and other appropriate agents.

可向藥師詢問的問題

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Elvitegravir / cobicistat / emtricitabine / tenofovir df 與 Raltegravir 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Elvitegravir / cobicistat / emtricitabine / tenofovir df with Raltegravir?

MediHelp rates the interaction as contraindicated. Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The elvitegravir-containing product is a complete single-tablet regimen, and adding raltegravir duplicates integrase inhibitor therapy with no established benefit. Safety and efficacy of this combination have not been studied.

How serious is the interaction between Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use the complete regimen alone or build a regimen with raltegravir and other appropriate agents.

What other medicines interact with Raltegravir?

MediHelp also lists interactions of Raltegravir with, for example, Aluminum hydroxide / magnesium carbonate, Aluminum hydroxide / magnesium trisilicate, Aluminum hydroxide. The full list is on the Raltegravir page.

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