藥物交互作用
Cabotegravir + Raltegravir
嚴重程度: 嚴重
Cabotegravir and Raltegravir: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Both are HIV integrase strand transfer inhibitors, so combining them is therapeutically duplicative. Cabotegravir with rilpivirine is intended as a complete regimen and adding raltegravir offers no established benefit.
用白話說明這項交互作用的意義
Cabotegravir and Raltegravir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cabotegravir belongs to Anti Virals; Raltegravir belongs to Anti Virals.
為什麼會發生
Pharmacodynamic duplication of integrase inhibitor therapy, with no established combination benefit.
處置方式
Do not combine; use one integrase inhibitor within a complete regimen. Choose either raltegravir-based therapy or cabotegravir plus rilpivirine.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Raltegravir 的其他交互作用
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Raltegravir 禁忌併用
- Aluminum hydroxide / magnesium carbonate + Raltegravir 嚴重
- Aluminum hydroxide / magnesium trisilicate + Raltegravir 嚴重
- Aluminum hydroxide + Raltegravir 嚴重
- Atidarsagene autotemcel + Raltegravir 嚴重
- Betibeglogene autotemcel + Raltegravir 嚴重
Cabotegravir 的其他交互作用
常見問題
Can I take Cabotegravir with Raltegravir?
MediHelp rates the interaction as major. Cabotegravir and Raltegravir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both are HIV integrase strand transfer inhibitors, so combining them is therapeutically duplicative. Cabotegravir with rilpivirine is intended as a complete regimen and adding raltegravir offers no established benefit.
How serious is the interaction between Cabotegravir and Raltegravir?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use one integrase inhibitor within a complete regimen. Choose either raltegravir-based therapy or cabotegravir plus rilpivirine.
What other medicines interact with Raltegravir?
MediHelp also lists interactions of Raltegravir with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Aluminum hydroxide / magnesium carbonate, Aluminum hydroxide / magnesium trisilicate. The full list is on the Raltegravir page.
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