藥物交互作用
Elvitegravir / cobicistat / emtricitabine / tenofovir df + Stavudine
嚴重程度: 禁忌併用
Elvitegravir / cobicistat / emtricitabine / tenofovir df and Stavudine: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
This fixed-dose product is a complete HIV regimen and is not intended for use with other antiretrovirals. Adding stavudine duplicates the nucleoside backbone and increases risks of neuropathy, lipoatrophy and lactic acidosis without benefit.
用白話說明這項交互作用的意義
Elvitegravir / cobicistat / emtricitabine / tenofovir df and Stavudine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Therapeutic duplication of nucleoside reverse transcriptase inhibitors, with additive mitochondrial toxicity.
處置方式
Do not co-administer; stavudine should be stopped if the single-tablet regimen is used.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Stavudine 的其他交互作用
常見問題
Can I take Elvitegravir / cobicistat / emtricitabine / tenofovir df with Stavudine?
MediHelp rates the interaction as contraindicated. Elvitegravir / cobicistat / emtricitabine / tenofovir df and Stavudine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This fixed-dose product is a complete HIV regimen and is not intended for use with other antiretrovirals. Adding stavudine duplicates the nucleoside backbone and increases risks of neuropathy, lipoatrophy and lactic acidosis without benefit.
How serious is the interaction between Elvitegravir / cobicistat / emtricitabine / tenofovir df and Stavudine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; stavudine should be stopped if the single-tablet regimen is used.
What other medicines interact with Stavudine?
MediHelp also lists interactions of Stavudine with, for example, Didanosine, Hydroxycarbamide, Zidovudine. The full list is on the Stavudine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
