藥物交互作用
Factor ix + Tranexamic acid
嚴重程度: 嚴重
Factor ix and Tranexamic acid: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Factor IX products can be thrombogenic, particularly prothrombin complex concentrates, and tranexamic acid blocks fibrinolysis. Using both together increases the chance of venous or arterial thrombosis.
用白話說明這項交互作用的意義
Factor ix and Tranexamic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Factor ix belongs to Cardiovascular; Tranexamic acid belongs to Cardiovascular.
為什麼會發生
Additive procoagulant effects: antifibrinolysis plus factor replacement
處置方式
Use together only when needed (e.g. dental procedures in haemophilia B), at lowest effective doses with thrombosis monitoring.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Tranexamic acid 的其他交互作用
Factor ix 的其他交互作用
常見問題
Can I take Factor ix with Tranexamic acid?
MediHelp rates the interaction as major. Factor ix and Tranexamic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Factor IX products can be thrombogenic, particularly prothrombin complex concentrates, and tranexamic acid blocks fibrinolysis. Using both together increases the chance of venous or arterial thrombosis.
How serious is the interaction between Factor ix and Tranexamic acid?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use together only when needed (e.g. dental procedures in haemophilia B), at lowest effective doses with thrombosis monitoring.
What other medicines interact with Tranexamic acid?
MediHelp also lists interactions of Tranexamic acid with, for example, Dienogest / estradiol valerate, Ethinyl estradiol-drospirenone, Ethinyl estradiol-levonorgestrel. The full list is on the Tranexamic acid page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。