藥物交互作用
Famciclovir + Tenofovir df
嚴重程度: 中度
Famciclovir and Tenofovir df: moderate interaction.
最後更新
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摘要
Penciclovir, the active metabolite of famciclovir, and tenofovir are both cleared renally including tubular secretion. Co-administration may raise levels of either drug, and tenofovir adds nephrotoxic potential.
用白話說明這項交互作用的意義
Famciclovir and Tenofovir df can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Competition for renal tubular secretion and possible additive renal effects.
處置方式
Monitor serum creatinine and phosphate periodically. Adjust the famciclovir dose to renal function.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Famciclovir 的其他交互作用
常見問題
Can I take Famciclovir with Tenofovir df?
MediHelp rates the interaction as moderate. Famciclovir and Tenofovir df can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Penciclovir, the active metabolite of famciclovir, and tenofovir are both cleared renally including tubular secretion. Co-administration may raise levels of either drug, and tenofovir adds nephrotoxic potential.
How serious is the interaction between Famciclovir and Tenofovir df?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and phosphate periodically. Adjust the famciclovir dose to renal function.
What other medicines interact with Famciclovir?
MediHelp also lists interactions of Famciclovir with, for example, Talimogene laherparepvec, Varicella virus vaccine live, Zoster vaccine live. The full list is on the Famciclovir page.
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