藥物交互作用
Famciclovir + Probenecid
嚴重程度: 輕微
Famciclovir and Probenecid: minor interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Probenecid reduces the renal secretion of penciclovir, the active metabolite of famciclovir, increasing its plasma levels. The change is usually modest and rarely requires action.
用白話說明這項交互作用的意義
Famciclovir and Probenecid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Famciclovir belongs to Anti Virals; Probenecid belongs to Genitourinary.
為什麼會發生
Probenecid inhibits renal tubular organic anion transport, reducing penciclovir elimination.
處置方式
No routine dose adjustment is needed. Monitor for adverse effects such as headache or nausea, and in renal impairment consider dose reduction per labeling.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Probenecid 的其他交互作用
Famciclovir 的其他交互作用
常見問題
Can I take Famciclovir with Probenecid?
MediHelp rates the interaction as minor. Famciclovir and Probenecid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Probenecid reduces the renal secretion of penciclovir, the active metabolite of famciclovir, increasing its plasma levels. The change is usually modest and rarely requires action.
How serious is the interaction between Famciclovir and Probenecid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose adjustment is needed. Monitor for adverse effects such as headache or nausea, and in renal impairment consider dose reduction per labeling.
What other medicines interact with Probenecid?
MediHelp also lists interactions of Probenecid with, for example, Ketorolac intranasal, Ketorolac, Baricitinib. The full list is on the Probenecid page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
