藥物交互作用
Foscarnet + Pimozide
嚴重程度: 禁忌併用
Foscarnet and Pimozide: contraindicated interaction.
最後更新
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摘要
Pimozide is a strongly QT-prolonging antipsychotic with documented torsades de pointes risk, and foscarnet adds QT prolongation and electrolyte disturbances. The combination could precipitate life-threatening arrhythmia.
用白話說明這項交互作用的意義
Foscarnet and Pimozide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Foscarnet belongs to Anti Virals; Pimozide belongs to Central Nervous System.
為什麼會發生
Additive QT prolongation, amplified by foscarnet-induced hypocalcemia, hypomagnesemia and hypokalemia.
處置方式
Do not combine; use an alternative to pimozide for the duration of foscarnet therapy.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Foscarnet 的其他交互作用
Pimozide 的其他交互作用
常見問題
Can I take Foscarnet with Pimozide?
MediHelp rates the interaction as contraindicated. Foscarnet and Pimozide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Pimozide is a strongly QT-prolonging antipsychotic with documented torsades de pointes risk, and foscarnet adds QT prolongation and electrolyte disturbances. The combination could precipitate life-threatening arrhythmia.
How serious is the interaction between Foscarnet and Pimozide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use an alternative to pimozide for the duration of foscarnet therapy.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Thioridazine, Vandetanib. The full list is on the Foscarnet page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。