藥物交互作用
Foscarnet + Vandetanib
嚴重程度: 禁忌併用
Foscarnet and Vandetanib: contraindicated interaction.
最後更新
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摘要
Vandetanib carries a boxed warning for QT prolongation, torsades de pointes and sudden death. Foscarnet adds QT liability and may cause electrolyte disturbances, making the combination particularly hazardous.
用白話說明這項交互作用的意義
Foscarnet and Vandetanib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Foscarnet belongs to Anti Virals; Vandetanib belongs to Oncology.
為什麼會發生
Additive QT prolongation, with foscarnet-induced hypocalcemia, hypomagnesemia or hypokalemia further increasing risk.
處置方式
Avoid the combination; choose an alternative antiviral or defer vandetanib while foscarnet is needed. If unavoidable, monitor ECG and electrolytes very frequently and correct abnormalities immediately.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Foscarnet 的其他交互作用
Vandetanib 的其他交互作用
常見問題
Can I take Foscarnet with Vandetanib?
MediHelp rates the interaction as contraindicated. Foscarnet and Vandetanib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Vandetanib carries a boxed warning for QT prolongation, torsades de pointes and sudden death. Foscarnet adds QT liability and may cause electrolyte disturbances, making the combination particularly hazardous.
How serious is the interaction between Foscarnet and Vandetanib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; choose an alternative antiviral or defer vandetanib while foscarnet is needed. If unavoidable, monitor ECG and electrolytes very frequently and correct abnormalities immediately.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
