藥物交互作用
Glipizide + Metreleptin
嚴重程度: 中度
Glipizide and Metreleptin: moderate interaction.
最後更新
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摘要
Metreleptin improves insulin sensitivity and lowers glucose, so with a sulfonylurea it can cause hypoglycemia. Patients may need substantial reductions in secretagogue dose.
用白話說明這項交互作用的意義
Glipizide and Metreleptin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Glipizide belongs to Endocrine; Metreleptin belongs to Endocrine.
為什麼會發生
Additive glucose-lowering effects via improved insulin sensitivity plus stimulated insulin secretion.
處置方式
Monitor blood glucose closely when starting metreleptin and consider reducing the glipizide dose in advance.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Glipizide 的其他交互作用
Metreleptin 的其他交互作用
常見問題
Can I take Glipizide with Metreleptin?
MediHelp rates the interaction as moderate. Glipizide and Metreleptin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Metreleptin improves insulin sensitivity and lowers glucose, so with a sulfonylurea it can cause hypoglycemia. Patients may need substantial reductions in secretagogue dose.
How serious is the interaction between Glipizide and Metreleptin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose closely when starting metreleptin and consider reducing the glipizide dose in advance.
What other medicines interact with Glipizide?
MediHelp also lists interactions of Glipizide with, for example, Disopyramide, Fluconazole, Insulin degludec-liraglutide. The full list is on the Glipizide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
