藥物交互作用
Hydroxyurea + Nelarabine
嚴重程度: 中度
Hydroxyurea and Nelarabine: moderate interaction.
最後更新
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摘要
Both drugs can suppress bone marrow. Combined use may worsen cytopenias, and nelarabine adds a separate risk of neurotoxicity.
用白話說明這項交互作用的意義
Hydroxyurea and Nelarabine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Hydroxyurea belongs to Miscellaneous; Nelarabine belongs to Oncology.
為什麼會發生
Additive myelosuppressive effects.
處置方式
Monitor blood counts frequently, and assess neurological status during nelarabine therapy. Adjust doses if marked cytopenias develop.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Hydroxyurea 的其他交互作用
Nelarabine 的其他交互作用
常見問題
Can I take Hydroxyurea with Nelarabine?
MediHelp rates the interaction as moderate. Hydroxyurea and Nelarabine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can suppress bone marrow. Combined use may worsen cytopenias, and nelarabine adds a separate risk of neurotoxicity.
How serious is the interaction between Hydroxyurea and Nelarabine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts frequently, and assess neurological status during nelarabine therapy. Adjust doses if marked cytopenias develop.
What other medicines interact with Hydroxyurea?
MediHelp also lists interactions of Hydroxyurea with, for example, Didanosine, Adenovirus types 4 and 7 live, Axicabtagene ciloleucel. The full list is on the Hydroxyurea page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。