藥物交互作用
Ifosfamide + Talimogene laherparepvec
嚴重程度: 禁忌併用
Ifosfamide and Talimogene laherparepvec: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Talimogene laherparepvec is a live, modified herpes simplex virus that replicates in tissue. In patients immunosuppressed by ifosfamide, this could lead to disseminated or serious herpetic infection.
用白話說明這項交互作用的意義
Ifosfamide and Talimogene laherparepvec are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ifosfamide belongs to Oncology; Talimogene laherparepvec belongs to Oncology.
為什麼會發生
Immunosuppression from chemotherapy impairs control of the replicating oncolytic herpes virus.
處置方式
Do not give talimogene laherparepvec to patients receiving ifosfamide or otherwise immunocompromised. Choose an alternative therapy and consult the oncology team.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Ifosfamide 的其他交互作用
Talimogene laherparepvec 的其他交互作用
常見問題
Can I take Ifosfamide with Talimogene laherparepvec?
MediHelp rates the interaction as contraindicated. Ifosfamide and Talimogene laherparepvec are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Talimogene laherparepvec is a live, modified herpes simplex virus that replicates in tissue. In patients immunosuppressed by ifosfamide, this could lead to disseminated or serious herpetic infection.
How serious is the interaction between Ifosfamide and Talimogene laherparepvec?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give talimogene laherparepvec to patients receiving ifosfamide or otherwise immunocompromised. Choose an alternative therapy and consult the oncology team.
What other medicines interact with Ifosfamide?
MediHelp also lists interactions of Ifosfamide with, for example, Adenovirus types 4 and 7 live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Ifosfamide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
