藥物交互作用
Influenza virus vaccine quadrivalent intranasal + Lomustine
嚴重程度: 禁忌併用
Influenza virus vaccine quadrivalent intranasal and Lomustine: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
The intranasal influenza vaccine contains live attenuated virus, which may replicate in patients immunosuppressed by lomustine and cause influenza illness. Protective response may also be impaired.
用白話說明這項交互作用的意義
Influenza virus vaccine quadrivalent intranasal and Lomustine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Cytotoxic immunosuppression impairs control of live vaccine virus replication and reduces the immune response.
處置方式
Do not use the live intranasal vaccine; give an inactivated injectable influenza vaccine instead, ideally timed away from the nadir of myelosuppression.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Lomustine 的其他交互作用
常見問題
Can I take Influenza virus vaccine quadrivalent intranasal with Lomustine?
MediHelp rates the interaction as contraindicated. Influenza virus vaccine quadrivalent intranasal and Lomustine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which may replicate in patients immunosuppressed by lomustine and cause influenza illness. Protective response may also be impaired.
How serious is the interaction between Influenza virus vaccine quadrivalent intranasal and Lomustine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use the live intranasal vaccine; give an inactivated injectable influenza vaccine instead, ideally timed away from the nadir of myelosuppression.
What other medicines interact with Lomustine?
MediHelp also lists interactions of Lomustine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Measles mumps and rubella vaccine. The full list is on the Lomustine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
