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藥物交互作用

Lomustine + Measles mumps and rubella vaccine

嚴重程度: 禁忌併用

Lomustine and Measles mumps and rubella vaccine: contraindicated interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Lomustine is a myelosuppressive cytotoxic agent, and live vaccine replication may be uncontrolled, risking disseminated vaccine-strain infection. The vaccine response may also be inadequate.

用白話說明這項交互作用的意義

Lomustine and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Lomustine belongs to Oncology; Measles mumps and rubella vaccine belongs to Miscellaneous.

證據等級: Moderate

為什麼會發生

Chemotherapy-induced immunosuppression permits unchecked replication of live attenuated virus.

處置方式

Do not give live vaccines during chemotherapy; defer until immune recovery, typically at least 3 months after stopping.

可向藥師詢問的問題

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Lomustine 與 Measles mumps and rubella vaccine 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Lomustine with Measles mumps and rubella vaccine?

MediHelp rates the interaction as contraindicated. Lomustine and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Lomustine is a myelosuppressive cytotoxic agent, and live vaccine replication may be uncontrolled, risking disseminated vaccine-strain infection. The vaccine response may also be inadequate.

How serious is the interaction between Lomustine and Measles mumps and rubella vaccine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during chemotherapy; defer until immune recovery, typically at least 3 months after stopping.

What other medicines interact with Measles mumps and rubella vaccine?

MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.

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