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藥物交互作用

Insulin aspart protamine / insulin aspart + Vitamin b3

嚴重程度: 中度

Insulin aspart protamine / insulin aspart and Vitamin b3: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Niacin at lipid-lowering doses can raise blood glucose and reduce insulin sensitivity. In patients using insulin this may lead to poorer glycemic control and higher insulin requirements.

用白話說明這項交互作用的意義

Insulin aspart protamine / insulin aspart and Vitamin b3 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

證據等級: Moderate

為什麼會發生

Niacin induces insulin resistance and impairs glucose tolerance, opposing the glucose-lowering effect of insulin.

處置方式

Monitor blood glucose more frequently when niacin is started, changed or stopped. Adjust the insulin dose as needed.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

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常見問題

Can I take Insulin aspart protamine / insulin aspart with Vitamin b3?

MediHelp rates the interaction as moderate. Insulin aspart protamine / insulin aspart and Vitamin b3 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Niacin at lipid-lowering doses can raise blood glucose and reduce insulin sensitivity. In patients using insulin this may lead to poorer glycemic control and higher insulin requirements.

How serious is the interaction between Insulin aspart protamine / insulin aspart and Vitamin b3?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more frequently when niacin is started, changed or stopped. Adjust the insulin dose as needed.

What other medicines interact with Vitamin b3?

MediHelp also lists interactions of Vitamin b3 with, for example, Lovastatin, Simvastatin, Atorvastatin. The full list is on the Vitamin b3 page.

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