藥物交互作用
Insulin degludec / insulin aspart + Rosiglitazone
嚴重程度: 嚴重
Insulin degludec / insulin aspart and Rosiglitazone: major interaction.
最後更新
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摘要
Rosiglitazone and insulin additively lower glucose, which can cause hypoglycemia. The combination also increases the risk of fluid retention, edema and heart failure.
用白話說明這項交互作用的意義
Insulin degludec / insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive glucose-lowering effects, and combined sodium and fluid retention from thiazolidinedione and insulin.
處置方式
Monitor glucose and reduce insulin dose if hypoglycemia occurs. Watch for edema, weight gain and heart failure symptoms; labeling advises caution with this combination.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Rosiglitazone 的其他交互作用
常見問題
Can I take Insulin degludec / insulin aspart with Rosiglitazone?
MediHelp rates the interaction as major. Insulin degludec / insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone and insulin additively lower glucose, which can cause hypoglycemia. The combination also increases the risk of fluid retention, edema and heart failure.
How serious is the interaction between Insulin degludec / insulin aspart and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose and reduce insulin dose if hypoglycemia occurs. Watch for edema, weight gain and heart failure symptoms; labeling advises caution with this combination.
What other medicines interact with Rosiglitazone?
MediHelp also lists interactions of Rosiglitazone with, for example, Insulin aspart protamine / insulin aspart, Insulin aspart-insulin aspart protamine, Insulin aspart. The full list is on the Rosiglitazone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
