藥物交互作用
Insulin aspart + Rosiglitazone
嚴重程度: 嚴重
Insulin aspart and Rosiglitazone: major interaction.
最後更新
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摘要
Rosiglitazone with insulin increases the risk of edema, heart failure and possibly ischemic cardiac events, and the glucose-lowering effects are additive. Hypoglycemia may occur.
用白話說明這項交互作用的意義
Insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin aspart belongs to Endocrine; Rosiglitazone belongs to Endocrine.
為什麼會發生
PPAR-gamma-mediated renal sodium and fluid retention compounded by insulin, plus additive glucose lowering.
處置方式
Monitor for edema, rapid weight gain and heart failure symptoms; avoid in patients with heart failure. Reduce the insulin dose if hypoglycemia occurs.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Insulin aspart 的其他交互作用
Rosiglitazone 的其他交互作用
- Insulin aspart protamine / insulin aspart + Rosiglitazone 嚴重
- Insulin aspart-insulin aspart protamine + Rosiglitazone 嚴重
- Insulin degludec / insulin aspart + Rosiglitazone 嚴重
- Insulin degludec-insulin aspart + Rosiglitazone 嚴重
- Insulin degludec-liraglutide + Rosiglitazone 嚴重
- Insulin degludec + Rosiglitazone 嚴重
常見問題
Can I take Insulin aspart with Rosiglitazone?
MediHelp rates the interaction as major. Insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone with insulin increases the risk of edema, heart failure and possibly ischemic cardiac events, and the glucose-lowering effects are additive. Hypoglycemia may occur.
How serious is the interaction between Insulin aspart and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for edema, rapid weight gain and heart failure symptoms; avoid in patients with heart failure. Reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin aspart?
MediHelp also lists interactions of Insulin aspart with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin aspart page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
