藥物交互作用
Insulin degludec-insulin aspart + Rosiglitazone
嚴重程度: 嚴重
Insulin degludec-insulin aspart and Rosiglitazone: major interaction.
最後更新
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摘要
Rosiglitazone combined with insulin increases glucose lowering and the risk of hypoglycemia. The combination markedly raises the risk of edema and heart failure, and labeling advises against its use with insulin.
用白話說明這項交互作用的意義
Insulin degludec-insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin degludec-insulin aspart belongs to Endocrine; Rosiglitazone belongs to Endocrine.
為什麼會發生
Rosiglitazone increases insulin sensitivity and causes fluid retention, adding to insulin effect and cardiac volume load.
處置方式
Avoid combining where possible; if used, reduce insulin as needed and monitor for edema, weight gain and heart failure.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Insulin degludec-insulin aspart 的其他交互作用
Rosiglitazone 的其他交互作用
常見問題
Can I take Insulin degludec-insulin aspart with Rosiglitazone?
MediHelp rates the interaction as major. Insulin degludec-insulin aspart and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone combined with insulin increases glucose lowering and the risk of hypoglycemia. The combination markedly raises the risk of edema and heart failure, and labeling advises against its use with insulin.
How serious is the interaction between Insulin degludec-insulin aspart and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where possible; if used, reduce insulin as needed and monitor for edema, weight gain and heart failure.
What other medicines interact with Insulin degludec-insulin aspart?
MediHelp also lists interactions of Insulin degludec-insulin aspart with, for example, Chlorpropamide, Clozapine, Diazoxide. The full list is on the Insulin degludec-insulin aspart page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
