藥物交互作用
Insulin neutral human + Rosiglitazone
嚴重程度: 嚴重
Insulin neutral human and Rosiglitazone: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Rosiglitazone with insulin increases the risk of fluid retention, edema, heart failure and hypoglycemia. The combination also carries a labeled cardiovascular concern, particularly in patients with cardiac risk.
用白話說明這項交互作用的意義
Insulin neutral human and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin neutral human belongs to Endocrine; Rosiglitazone belongs to Endocrine.
為什麼會發生
Additive improvement in insulin sensitivity plus PPAR-gamma-mediated sodium and fluid retention, which insulin can aggravate.
處置方式
Avoid the combination in patients with heart failure or high cardiovascular risk; if used, reduce the insulin dose as needed and monitor weight, edema and cardiac symptoms.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Insulin neutral human 的其他交互作用
Rosiglitazone 的其他交互作用
- Insulin aspart protamine / insulin aspart + Rosiglitazone 嚴重
- Insulin aspart-insulin aspart protamine + Rosiglitazone 嚴重
- Insulin aspart + Rosiglitazone 嚴重
- Insulin degludec / insulin aspart + Rosiglitazone 嚴重
- Insulin degludec-insulin aspart + Rosiglitazone 嚴重
- Insulin degludec-liraglutide + Rosiglitazone 嚴重
常見問題
Can I take Insulin neutral human with Rosiglitazone?
MediHelp rates the interaction as major. Insulin neutral human and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone with insulin increases the risk of fluid retention, edema, heart failure and hypoglycemia. The combination also carries a labeled cardiovascular concern, particularly in patients with cardiac risk.
How serious is the interaction between Insulin neutral human and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination in patients with heart failure or high cardiovascular risk; if used, reduce the insulin dose as needed and monitor weight, edema and cardiac symptoms.
What other medicines interact with Insulin neutral human?
MediHelp also lists interactions of Insulin neutral human with, for example, Chlorpropamide, Ethanol, Mecasermin. The full list is on the Insulin neutral human page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。