藥物交互作用
Itraconazole + Ticagrelor
嚴重程度: 禁忌併用
Itraconazole and Ticagrelor: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Itraconazole is a strong CYP3A4 and P-glycoprotein inhibitor and raises ticagrelor exposure markedly. Bleeding risk and ticagrelor adverse effects, including dyspnoea, increase.
用白話說明這項交互作用的意義
Itraconazole and Ticagrelor are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Itraconazole belongs to Anti Fungals; Ticagrelor belongs to Cardiovascular.
為什麼會發生
Strong CYP3A4/P-gp inhibition markedly raises ticagrelor exposure
處置方式
Contraindicated; use an alternative P2Y12 inhibitor or antifungal.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Itraconazole 的其他交互作用
Ticagrelor 的其他交互作用
常見問題
Can I take Itraconazole with Ticagrelor?
MediHelp rates the interaction as contraindicated. Itraconazole and Ticagrelor are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Itraconazole is a strong CYP3A4 and P-glycoprotein inhibitor and raises ticagrelor exposure markedly. Bleeding risk and ticagrelor adverse effects, including dyspnoea, increase.
How serious is the interaction between Itraconazole and Ticagrelor?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Contraindicated; use an alternative P2Y12 inhibitor or antifungal.
What other medicines interact with Itraconazole?
MediHelp also lists interactions of Itraconazole with, for example, Alfuzosin, Alprazolam, Avanafil. The full list is on the Itraconazole page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
