藥物交互作用
Abciximab + Ticagrelor
嚴重程度: 嚴重
Abciximab and Ticagrelor: major interaction.
最後更新
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摘要
Ticagrelor with a glycoprotein IIb/IIIa inhibitor produces strong combined platelet inhibition and increases the risk of major bleeding. This pairing is sometimes used deliberately during PCI but requires care.
用白話說明這項交互作用的意義
Abciximab and Ticagrelor can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Abciximab belongs to Cardiovascular; Ticagrelor belongs to Cardiovascular.
為什麼會發生
Additive antiplatelet effects via P2Y12 blockade and GP IIb/IIIa receptor blockade.
處置方式
Use only when clearly indicated, such as during PCI, and monitor hemoglobin, platelet count and bleeding signs. Limit duration of the GP IIb/IIIa infusion.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Ticagrelor 的其他交互作用
Abciximab 的其他交互作用
常見問題
Can I take Abciximab with Ticagrelor?
MediHelp rates the interaction as major. Abciximab and Ticagrelor can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ticagrelor with a glycoprotein IIb/IIIa inhibitor produces strong combined platelet inhibition and increases the risk of major bleeding. This pairing is sometimes used deliberately during PCI but requires care.
How serious is the interaction between Abciximab and Ticagrelor?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only when clearly indicated, such as during PCI, and monitor hemoglobin, platelet count and bleeding signs. Limit duration of the GP IIb/IIIa infusion.
What other medicines interact with Ticagrelor?
MediHelp also lists interactions of Ticagrelor with, for example, Itraconazole, Ketoconazole, Levoketoconazole. The full list is on the Ticagrelor page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
