藥物交互作用
Lamivudine + Ribavirin
嚴重程度: 輕微
Lamivudine and Ribavirin: minor interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Ribavirin and lamivudine have no established pharmacokinetic interaction, and the concern is largely theoretical additive mitochondrial toxicity and lactic acidosis. Clinical data in HIV and hepatitis C coinfection have not shown a significant problem.
用白話說明這項交互作用的意義
Lamivudine and Ribavirin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lamivudine belongs to Anti Virals; Ribavirin belongs to Anti Virals.
為什麼會發生
Theoretical additive mitochondrial toxicity; no established pharmacokinetic interaction.
處置方式
No dose change is needed; monitor for symptoms of lactic acidosis, and monitor hemoglobin and liver function during ribavirin therapy.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Ribavirin 的其他交互作用
Lamivudine 的其他交互作用
常見問題
Can I take Lamivudine with Ribavirin?
MediHelp rates the interaction as minor. Lamivudine and Ribavirin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ribavirin and lamivudine have no established pharmacokinetic interaction, and the concern is largely theoretical additive mitochondrial toxicity and lactic acidosis. Clinical data in HIV and hepatitis C coinfection have not shown a significant problem.
How serious is the interaction between Lamivudine and Ribavirin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed; monitor for symptoms of lactic acidosis, and monitor hemoglobin and liver function during ribavirin therapy.
What other medicines interact with Ribavirin?
MediHelp also lists interactions of Ribavirin with, for example, Didanosine, Stavudine, Zidovudine. The full list is on the Ribavirin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
