藥物交互作用
Didanosine + Ribavirin
嚴重程度: 禁忌併用
Didanosine and Ribavirin: contraindicated interaction.
最後更新
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摘要
Ribavirin increases intracellular didanosine triphosphate and mitochondrial toxicity. This raises the risk of pancreatitis, peripheral neuropathy, lactic acidosis and hepatic failure.
用白話說明這項交互作用的意義
Didanosine and Ribavirin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Didanosine belongs to Anti Virals; Ribavirin belongs to Anti Virals.
為什麼會發生
Increased didanosine mitochondrial toxicity
處置方式
Contraindicated by labelling; use another antiretroviral and avoid the combination.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Ribavirin 的其他交互作用
Didanosine 的其他交互作用
常見問題
Can I take Didanosine with Ribavirin?
MediHelp rates the interaction as contraindicated. Didanosine and Ribavirin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ribavirin increases intracellular didanosine triphosphate and mitochondrial toxicity. This raises the risk of pancreatitis, peripheral neuropathy, lactic acidosis and hepatic failure.
How serious is the interaction between Didanosine and Ribavirin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Contraindicated by labelling; use another antiretroviral and avoid the combination.
What other medicines interact with Ribavirin?
MediHelp also lists interactions of Ribavirin with, for example, Stavudine, Zidovudine, Abacavir. The full list is on the Ribavirin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
