藥物交互作用
Lapatinib + Oteseconazole
嚴重程度: 中度
Lapatinib and Oteseconazole: moderate interaction.
最後更新
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摘要
Oteseconazole inhibits BCRP and may increase lapatinib exposure, raising the risk of diarrhea, rash and hepatotoxicity.
用白話說明這項交互作用的意義
Lapatinib and Oteseconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lapatinib belongs to Oncology; Oteseconazole belongs to Anti Fungals.
為什麼會發生
Inhibition of BCRP-mediated efflux of lapatinib by oteseconazole.
處置方式
Monitor for lapatinib toxicity and liver function. Consider a lapatinib dose reduction if adverse effects occur.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Lapatinib 的其他交互作用
Oteseconazole 的其他交互作用
常見問題
Can I take Lapatinib with Oteseconazole?
MediHelp rates the interaction as moderate. Lapatinib and Oteseconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oteseconazole inhibits BCRP and may increase lapatinib exposure, raising the risk of diarrhea, rash and hepatotoxicity.
How serious is the interaction between Lapatinib and Oteseconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for lapatinib toxicity and liver function. Consider a lapatinib dose reduction if adverse effects occur.
What other medicines interact with Lapatinib?
MediHelp also lists interactions of Lapatinib with, for example, Dofetilide, Ibutilide, Pimozide. The full list is on the Lapatinib page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
