藥物交互作用
Glyburide-metformin + Oteseconazole
嚴重程度: 中度
Glyburide-metformin and Oteseconazole: moderate interaction.
最後更新
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摘要
Oteseconazole inhibits BCRP and may raise glyburide exposure. Higher glyburide levels could increase hypoglycemia risk.
用白話說明這項交互作用的意義
Glyburide-metformin and Oteseconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Glyburide-metformin belongs to Endocrine; Oteseconazole belongs to Anti Fungals.
為什麼會發生
BCRP inhibition by oteseconazole reduces glyburide efflux and clearance.
處置方式
Monitor blood glucose during oteseconazole therapy. Use the lowest effective glyburide dose and reduce it if hypoglycemia occurs.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Glyburide-metformin 的其他交互作用
Oteseconazole 的其他交互作用
常見問題
Can I take Glyburide-metformin with Oteseconazole?
MediHelp rates the interaction as moderate. Glyburide-metformin and Oteseconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oteseconazole inhibits BCRP and may raise glyburide exposure. Higher glyburide levels could increase hypoglycemia risk.
How serious is the interaction between Glyburide-metformin and Oteseconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose during oteseconazole therapy. Use the lowest effective glyburide dose and reduce it if hypoglycemia occurs.
What other medicines interact with Glyburide-metformin?
MediHelp also lists interactions of Glyburide-metformin with, for example, Bosentan, Cholic acid, Clarithromycin. The full list is on the Glyburide-metformin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
