藥物交互作用
Fluvastatin + Oteseconazole
嚴重程度: 中度
Fluvastatin and Oteseconazole: moderate interaction.
最後更新
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摘要
Oteseconazole inhibits BCRP and can raise levels of BCRP substrates such as fluvastatin. Increased statin exposure raises the risk of muscle toxicity.
用白話說明這項交互作用的意義
Fluvastatin and Oteseconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fluvastatin belongs to Cardiovascular; Oteseconazole belongs to Anti Fungals.
為什麼會發生
Oteseconazole inhibits BCRP, increasing fluvastatin absorption and reducing efflux.
處置方式
Start with the lowest fluvastatin dose or reduce the dose, and monitor for myopathy symptoms.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Fluvastatin 的其他交互作用
Oteseconazole 的其他交互作用
常見問題
Can I take Fluvastatin with Oteseconazole?
MediHelp rates the interaction as moderate. Fluvastatin and Oteseconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oteseconazole inhibits BCRP and can raise levels of BCRP substrates such as fluvastatin. Increased statin exposure raises the risk of muscle toxicity.
How serious is the interaction between Fluvastatin and Oteseconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start with the lowest fluvastatin dose or reduce the dose, and monitor for myopathy symptoms.
What other medicines interact with Fluvastatin?
MediHelp also lists interactions of Fluvastatin with, for example, Cyclosporine, Cyclosporin, Gemfibrozil. The full list is on the Fluvastatin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
