藥物交互作用
Measles vaccine + Mycophenolate mofetil
嚴重程度: 禁忌併用
Measles vaccine and Mycophenolate mofetil: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Measles vaccine is live attenuated and can cause disseminated vaccine-strain infection in patients with significant immunosuppression. Mycophenolate may also reduce the immune response.
用白話說明這項交互作用的意義
Measles vaccine and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Impaired T and B cell function allows uncontrolled replication of live attenuated virus.
處置方式
Avoid the vaccine during mycophenolate therapy. Give it at least 4 weeks before starting treatment if possible, and use immunoglobulin prophylaxis after exposure.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Mycophenolate mofetil 的其他交互作用
- Adenovirus types 4 and 7 live + Mycophenolate mofetil 禁忌併用
- Bcg vaccine live + Mycophenolate mofetil 禁忌併用
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil 禁忌併用
- Measles mumps and rubella vaccine live + Mycophenolate mofetil 禁忌併用
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil 禁忌併用
- Mycophenolate mofetil + Rotavirus oral vaccine live 禁忌併用
常見問題
Can I take Measles vaccine with Mycophenolate mofetil?
MediHelp rates the interaction as contraindicated. Measles vaccine and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated and can cause disseminated vaccine-strain infection in patients with significant immunosuppression. Mycophenolate may also reduce the immune response.
How serious is the interaction between Measles vaccine and Mycophenolate mofetil?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the vaccine during mycophenolate therapy. Give it at least 4 weeks before starting treatment if possible, and use immunoglobulin prophylaxis after exposure.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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