藥物交互作用
Mycophenolate mofetil + Rotavirus oral vaccine live
嚴重程度: 禁忌併用
Mycophenolate mofetil and Rotavirus oral vaccine live: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Rotavirus vaccine is live attenuated, and replication may be prolonged or cause disease in patients with significant immunosuppression. Mycophenolate exposure, including in infants born to treated mothers, raises this concern.
用白話說明這項交互作用的意義
Mycophenolate mofetil and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Impaired immune control allows replication of live attenuated rotavirus.
處置方式
Avoid the live vaccine in patients on mycophenolate. For infants exposed in utero, follow specialist advice on timing.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Mycophenolate mofetil 的其他交互作用
- Adenovirus types 4 and 7 live + Mycophenolate mofetil 禁忌併用
- Bcg vaccine live + Mycophenolate mofetil 禁忌併用
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil 禁忌併用
- Measles mumps and rubella vaccine live + Mycophenolate mofetil 禁忌併用
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil 禁忌併用
- Measles vaccine + Mycophenolate mofetil 禁忌併用
常見問題
Can I take Mycophenolate mofetil with Rotavirus oral vaccine live?
MediHelp rates the interaction as contraindicated. Mycophenolate mofetil and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Rotavirus vaccine is live attenuated, and replication may be prolonged or cause disease in patients with significant immunosuppression. Mycophenolate exposure, including in infants born to treated mothers, raises this concern.
How serious is the interaction between Mycophenolate mofetil and Rotavirus oral vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live vaccine in patients on mycophenolate. For infants exposed in utero, follow specialist advice on timing.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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