藥物交互作用
Megestrol + Warfarin
嚴重程度: 中度
Megestrol and Warfarin: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Increases in INR and bleeding have been reported in patients on warfarin who start megestrol. The reports are limited, and the effect varies between patients.
用白話說明這項交互作用的意義
Megestrol and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Megestrol belongs to Oncology; Warfarin belongs to Cardiovascular.
為什麼會發生
The mechanism is not established; altered warfarin metabolism or protein binding has been proposed.
處置方式
Check INR within a week of starting or stopping megestrol and adjust the warfarin dose accordingly.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Warfarin 的其他交互作用
Megestrol 的其他交互作用
常見問題
Can I take Megestrol with Warfarin?
MediHelp rates the interaction as moderate. Megestrol and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Increases in INR and bleeding have been reported in patients on warfarin who start megestrol. The reports are limited, and the effect varies between patients.
How serious is the interaction between Megestrol and Warfarin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check INR within a week of starting or stopping megestrol and adjust the warfarin dose accordingly.
What other medicines interact with Warfarin?
MediHelp also lists interactions of Warfarin with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Warfarin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
