藥物交互作用
Insulin degludec-liraglutide + Megestrol
嚴重程度: 中度
Insulin degludec-liraglutide and Megestrol: moderate interaction.
最後更新
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摘要
Megestrol has glucocorticoid-like activity and can raise blood glucose, sometimes unmasking or worsening diabetes. This may reduce the effectiveness of insulin degludec and liraglutide.
用白話說明這項交互作用的意義
Insulin degludec-liraglutide and Megestrol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Insulin degludec-liraglutide belongs to Endocrine; Megestrol belongs to Oncology.
為什麼會發生
Progestin with glucocorticoid activity impairs glucose tolerance and insulin sensitivity.
處置方式
Monitor blood glucose during megestrol therapy and increase antidiabetic doses if hyperglycemia occurs.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Insulin degludec-liraglutide 的其他交互作用
Megestrol 的其他交互作用
常見問題
Can I take Insulin degludec-liraglutide with Megestrol?
MediHelp rates the interaction as moderate. Insulin degludec-liraglutide and Megestrol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Megestrol has glucocorticoid-like activity and can raise blood glucose, sometimes unmasking or worsening diabetes. This may reduce the effectiveness of insulin degludec and liraglutide.
How serious is the interaction between Insulin degludec-liraglutide and Megestrol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose during megestrol therapy and increase antidiabetic doses if hyperglycemia occurs.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
