藥物交互作用
Insulin degludec + Megestrol
嚴重程度: 中度
Insulin degludec and Megestrol: moderate interaction.
最後更新
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摘要
Megestrol, particularly at higher doses used for appetite stimulation, can raise blood glucose through glucocorticoid-like activity and reduce insulin effectiveness. Insulin requirements may rise.
用白話說明這項交互作用的意義
Insulin degludec and Megestrol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Insulin degludec belongs to Endocrine; Megestrol belongs to Oncology.
為什麼會發生
Megestrol has glucocorticoid-like activity that promotes insulin resistance and hyperglycemia, opposing insulin action.
處置方式
Monitor blood glucose when starting, adjusting or stopping megestrol and increase the insulin dose as needed. Reduce the insulin dose again after megestrol is discontinued.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Insulin degludec 的其他交互作用
Megestrol 的其他交互作用
常見問題
Can I take Insulin degludec with Megestrol?
MediHelp rates the interaction as moderate. Insulin degludec and Megestrol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Megestrol, particularly at higher doses used for appetite stimulation, can raise blood glucose through glucocorticoid-like activity and reduce insulin effectiveness. Insulin requirements may rise.
How serious is the interaction between Insulin degludec and Megestrol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting, adjusting or stopping megestrol and increase the insulin dose as needed. Reduce the insulin dose again after megestrol is discontinued.
What other medicines interact with Insulin degludec?
MediHelp also lists interactions of Insulin degludec with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin degludec page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
