藥品參考
Megestrol
Megestrol is a medicine in the class oncology. It is used for breast cancer.
- 藥物類別: Oncology
- 用途: breast cancer
最後更新
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重點資訊
- 藥物類別
- Oncology
- 常見劑型
- 錠劑
- 常見規格
- 160 mg
- 已知交互作用
- 9 (禁忌併用: 1 · 中度: 7 · 輕微: 1)
- 商品名
- 1
- 國家與市場
- 1
用途
作用方式
Progestin derivative with antiestrogenic properties; interferes with estrogen cycle, resulting in lower luteinizing hormone (LH) titer; antineoplastic properties may come from direct effect on endometrium through anti-LH effect mediated via pituitary
成人常用劑量（仿單摘要）
AIDS-Related Cachexia (Megace): 800 mg/day PO
懷孕與哺乳
- 懷孕
- Unsafe Avoid: progestogen; rats showed fewer live births and feminised male fetuses, and early-pregnancy progestogen exposure has been linked to hypospadias. UK label: not recommended in pregnancy. Women who could become pregnant should use contraception.
- 哺乳
- Unknown No LactMed or e-lactancia record. US and UK labels: stop breastfeeding during treatment because of possible effects on the newborn. Prefer not to breastfeed while taking it.
已通報的副作用
- Thrombophlebitis
- Hypertension
- Insomnia
- Mood swings
- Amenorrhea
- Rash
禁忌症
- Known or suspected pregnancy
- Acute thrombophlebitis, thromboembolic disorder, breast cancer
- Undiagnosed abnormal genital bleeding
哪些人需要特別留意
- Adrenal insufficiency may occur in patients receiving or being withdrawn from long-term megestrol treatment
- Megestrol is a progesterone derivative which may induce vaginal bleeding in women
- Cushing syndrome reported
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (9)
- Dofetilide + Megestrol Contraindicated
- Insulin degludec + Megestrol Moderate
- Insulin degludec / insulin aspart + Megestrol Moderate
- Insulin degludec-insulin aspart + Megestrol Moderate
- Insulin degludec-liraglutide + Megestrol Moderate
- Insulin inhaled + Megestrol Moderate
- Mavacamten + Megestrol Moderate
- Megestrol + Warfarin Moderate
- Maitake + Megestrol Minor
同類別的其他藥品
常見問題
What is Megestrol used for?
Megestrol is a medicine in the class oncology. It is used for Breast cancer, Cachexia, Endometrial carcinoma.
What side effects have been reported with Megestrol?
Thrombophlebitis, Hypertension, Insomnia, Mood swings, Amenorrhea, Rash.
Can Megestrol be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Avoid: progestogen; rats showed fewer live births and feminised male fetuses, and early-pregnancy progestogen exposure has been linked to hypospadias. UK label: not recommended in pregnancy. Women who could become pregnant should use contraception. Breastfeeding: Unknown. No LactMed or e-lactancia record. US and UK labels: stop breastfeeding during treatment because of possible effects on the newborn. Prefer not to breastfeed while taking it.
What does Megestrol interact with?
MediHelp lists 9 known interactions for Megestrol. Contraindicated: 1 · Moderate: 7 · Minor: 1. The most serious include Dofetilide, Insulin degludec, Insulin degludec / insulin aspart.
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