藥物交互作用
Nevirapine + Valoctocogene roxaparvovec
嚴重程度: 嚴重
Nevirapine and Valoctocogene roxaparvovec: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Valoctocogene roxaparvovec commonly causes elevated liver enzymes, and nevirapine is a known hepatotoxic drug. Combined use may increase the risk or severity of liver injury and could compromise the gene therapy outcome.
用白話說明這項交互作用的意義
Nevirapine and Valoctocogene roxaparvovec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Nevirapine belongs to Anti Virals; Valoctocogene roxaparvovec belongs to Miscellaneous.
為什麼會發生
Additive hepatotoxicity; nevirapine can cause hepatocellular injury independent of the gene therapy.
處置方式
Monitor ALT and other liver tests frequently after gene therapy. Prefer an alternative antiretroviral to nevirapine where possible.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Nevirapine 的其他交互作用
Valoctocogene roxaparvovec 的其他交互作用
常見問題
Can I take Nevirapine with Valoctocogene roxaparvovec?
MediHelp rates the interaction as major. Nevirapine and Valoctocogene roxaparvovec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Valoctocogene roxaparvovec commonly causes elevated liver enzymes, and nevirapine is a known hepatotoxic drug. Combined use may increase the risk or severity of liver injury and could compromise the gene therapy outcome.
How serious is the interaction between Nevirapine and Valoctocogene roxaparvovec?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ALT and other liver tests frequently after gene therapy. Prefer an alternative antiretroviral to nevirapine where possible.
What other medicines interact with Nevirapine?
MediHelp also lists interactions of Nevirapine with, for example, Elbasvir / grazoprevir, Ranolazine, St john's wort. The full list is on the Nevirapine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
