藥物交互作用
Prednisone + Radium-223 dichloride
嚴重程度: 禁忌併用
Prednisone and Radium-223 dichloride: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Prednisone is relevant here as the steroid given with abiraterone; that triple combination with radium-223 has shown more fractures and a mortality trend. Prednisone alone with radium-223 is not itself the identified concern.
用白話說明這項交互作用的意義
Prednisone and Radium-223 dichloride are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Prednisone belongs to Endocrine; Radium-223 dichloride belongs to Miscellaneous.
為什麼會發生
The mechanism is not established; additive bone toxicity has been proposed.
處置方式
Avoid radium-223 in patients receiving abiraterone with prednisone. Review need for steroids and bone protection if used separately.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Radium-223 dichloride 的其他交互作用
Prednisone 的其他交互作用
常見問題
Can I take Prednisone with Radium-223 dichloride?
MediHelp rates the interaction as contraindicated. Prednisone and Radium-223 dichloride are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Prednisone is relevant here as the steroid given with abiraterone; that triple combination with radium-223 has shown more fractures and a mortality trend. Prednisone alone with radium-223 is not itself the identified concern.
How serious is the interaction between Prednisone and Radium-223 dichloride?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid radium-223 in patients receiving abiraterone with prednisone. Review need for steroids and bone protection if used separately.
What other medicines interact with Radium-223 dichloride?
MediHelp also lists interactions of Radium-223 dichloride with, for example, Abiraterone, Prednisolone, Siponimod. The full list is on the Radium-223 dichloride page.
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