Drug reference
bupropion
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Atypical Antidepressant)
Mechanism of action
Not well understood; structurally unrelated to SSRIs, TCAs, MAOIs; does not inhibit the activity of monoamine oxidase or the reuptake of serotonin, Norepinephrine dopamine reuptake inhibitor; may act through dopaminergic or noradrenergic pathways.
Common side effects
- Dry mouth
- Headache
- Nausea
- Weight loss
- Insomnia, Agitation.
Known interactions (2)
- bupropion + phenelzine Contraindicated
- bupropion + tramadol Major
Related conditions
Frequently asked questions
What drug class is bupropion?
bupropion belongs to: Central Nervous System.
How does bupropion work?
Not well understood; structurally unrelated to SSRIs, TCAs, MAOIs; does not inhibit the activity of monoamine oxidase or the reuptake of serotonin, Norepinephrine dopamine reuptake inhibitor; may act through dopaminergic or noradrenergic pathways.
What are the common side effects of bupropion?
Dry mouth, Headache, Nausea, Weight loss, Insomnia, Agitation.
Which drugs interact with bupropion?
phenelzine, tramadol
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