Drug reference

vilazodone

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Central Nervous System (Atypical Antidepressant)

Mechanism of action

Mechanism of antidepressant effect is not fully understood, but may be related to serotonergic activity in the CNS through selective inhibition of serotonin reuptake; no effect on norepinephrine or dopamine reuptake Partial agonist of serotonergic 5-HT1A receptor whose activity may be altered in depression and anxiety

Common side effects

  • Insomnia
  • Dizziness
  • Vomiting
  • Fatigue
  • Nausea
  • Xerostomia
  • Diarrhea

Known interactions (1)

Related conditions

Frequently asked questions

What drug class is vilazodone?

vilazodone belongs to: Central Nervous System.

How does vilazodone work?

Mechanism of antidepressant effect is not fully understood, but may be related to serotonergic activity in the CNS through selective inhibition of serotonin reuptake; no effect on norepinephrine or dopamine reuptake Partial agonist of serotonergic 5-HT1A receptor whose activity may be altered in depression and anxiety

What are the common side effects of vilazodone?

Insomnia, Dizziness, Vomiting, Fatigue, Nausea, Xerostomia, Diarrhea

Which drugs interact with vilazodone?

isocarboxazid

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug reference