Drug reference

empagliflozin

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Endocrine (Glycosurics)

Mechanism of action

SGLT2 is expressed in the proximal renal tubules and is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen; SGLT2 inhibitors reduce glucose reabsorption and lower the renal threshold for glucose, thereby increasing urinary glucose excretion

Common side effects

  • Upper respiratory tract infection
  • Arthralgia
  • Female genital mycotic infections
  • Increased urination
  • Dyslipidemia
  • Urinary tract infection

Known interactions (3)

Related conditions

Frequently asked questions

What drug class is empagliflozin?

empagliflozin belongs to: Endocrine.

How does empagliflozin work?

SGLT2 is expressed in the proximal renal tubules and is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen; SGLT2 inhibitors reduce glucose reabsorption and lower the renal threshold for glucose, thereby increasing urinary glucose excretion

What are the common side effects of empagliflozin?

Upper respiratory tract infection, Arthralgia, Female genital mycotic infections, Increased urination, Dyslipidemia, Urinary tract infection

Which drugs interact with empagliflozin?

bisoprolol, Sulpiride, torsemide

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug reference