Drug reference

canagliflozin

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Endocrine (Glycosurics)

Mechanism of action

SGLT-2 inhibition lowers the renal glucose threshold (ie, the plasma glucose concentration which exceed the maximum glucose reabsorption capacity of the kidney); lowering the renal glucose threshold results in increased urinary glucose excretion

Common side effects

  • Constipation
  • Female genital mycotic infections
  • Thirst
  • Urinary tract infections
  • Increased urination
  • Male genital mycotic infections

Related conditions

Frequently asked questions

What drug class is canagliflozin?

canagliflozin belongs to: Endocrine.

How does canagliflozin work?

SGLT-2 inhibition lowers the renal glucose threshold (ie, the plasma glucose concentration which exceed the maximum glucose reabsorption capacity of the kidney); lowering the renal glucose threshold results in increased urinary glucose excretion

What are the common side effects of canagliflozin?

Constipation, Female genital mycotic infections, Thirst, Urinary tract infections, Increased urination, Male genital mycotic infections

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug reference