Drug reference
dapagliflozin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Endocrine (Glycosurics)
Mechanism of action
SGLT-2, expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen; SGLT2 inhibitors will reduce glucose reabsorption and lower the renal threshold for glucose, thereby increasing urinary glucose excretion
Common side effects
- Nasopharyngitis
- Back pain
- Female genital mycotic infections
- Renal impairment
- Urinary tract infection
Known interactions (1)
- dapagliflozin + sacubitril/valsartan Moderate
Related conditions
Frequently asked questions
What drug class is dapagliflozin?
dapagliflozin belongs to: Endocrine.
How does dapagliflozin work?
SGLT-2, expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen; SGLT2 inhibitors will reduce glucose reabsorption and lower the renal threshold for glucose, thereby increasing urinary glucose excretion
What are the common side effects of dapagliflozin?
Nasopharyngitis, Back pain, Female genital mycotic infections, Renal impairment, Urinary tract infection
Which drugs interact with dapagliflozin?
sacubitril/valsartan
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