Drug reference

cefotaxime

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Anti Bacterial (Cephalosporins)

Mechanism of action

Binds to penicillin-binding proteins and inhibits final transpeptidation step of peptidoglycan synthesis, resulting in cell-wall death; resists degradation by beta-lactamase; proper dosing and appropriate route of administration are determined by condition of patient, severity of infection, and susceptibility of microorganism.

Common side effects

  • Colitis
  • Fever
  • Eosinophilia
  • Elevated blood urea nitrogen (BUN) and creatinine
  • Elevated hepatic transaminases
  • Diarrhea

Contraindications

  • Documented hypersensitivity to drug or components

Related conditions

Frequently asked questions

What drug class is cefotaxime?

cefotaxime belongs to: Anti Bacterial.

How does cefotaxime work?

Binds to penicillin-binding proteins and inhibits final transpeptidation step of peptidoglycan synthesis, resulting in cell-wall death; resists degradation by beta-lactamase; proper dosing and appropriate route of administration are determined by condition of patient, severity of infection, and susceptibility of microorganism.

What are the common side effects of cefotaxime?

Colitis, Fever, Eosinophilia, Elevated blood urea nitrogen (BUN) and creatinine, Elevated hepatic transaminases, Diarrhea

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