Drug reference
clofazimine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Bacterial (Anti Leprosy)
Mechanism of action
Exerts a slow bactericidal effect on Mycobacterium leprae (Hansen’s bacillus); inhibits mycobacterial growth and binds preferentially to mycobacterial DNA. Also exerts anti-inflammatory properties in controlling erythema nodosum leprosum reactions; however, its precise mechanisms of action are unknown.
Common side effects
- Vomiting
- Skin discoloration
- Abdominal and epigastric pain,
- Ichthyosis and dry skin
- Diarrhea
Contraindications
- Contraindicated in patients with known hypersensitivity to clofazimine or any of the excipients of clofazimine
Known interactions (1)
Related conditions
Frequently asked questions
What drug class is clofazimine?
clofazimine belongs to: Anti Bacterial.
How does clofazimine work?
Exerts a slow bactericidal effect on Mycobacterium leprae (Hansen’s bacillus); inhibits mycobacterial growth and binds preferentially to mycobacterial DNA. Also exerts anti-inflammatory properties in controlling erythema nodosum leprosum reactions; however, its precise mechanisms of action are unknown.
What are the common side effects of clofazimine?
Vomiting, Skin discoloration, Abdominal and epigastric pain,, Ichthyosis and dry skin, Diarrhea
Which drugs interact with clofazimine?
clarithromycin
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