Drug interactions
azithromycin + hydroxychloroquine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Additive QT prolongation → arrhythmia risk.
Mechanism of action
IKr blockade additive.
Clinical management
Avoid co-use; monitor ECG.
Drug reference
References
Frequently asked questions
Can I take azithromycin with hydroxychloroquine?
The interaction is rated: Major. Additive QT prolongation → arrhythmia risk.
How serious is the interaction between azithromycin and hydroxychloroquine?
The interaction is rated: Major. Evidence level: Moderate.
How is the interaction between azithromycin and hydroxychloroquine managed?
Avoid co-use; monitor ECG.
Why do azithromycin and hydroxychloroquine interact?
IKr blockade additive.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.