Drug reference
fenofibrate
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Anti Hyperlipidemics)
Mechanism of action
Fenofibrate is a prodrug that is metabolized to the active moiety, fenofibric acid Activates peroxisome proliferator activated receptor-alpha (PPAR-alpha); increases lipolysis and elimination of triglyceride-rich particles from plasma by activating lipoprotein lipase and reduces Apo CIII production (lipoprotein lipase inhibitor)
Common side effects
- Back pain
- Increased LFT's
- Respiratory disorder
- Abdominal pain
Known interactions (1)
- fenofibrate + valproic acid Moderate
Related conditions
Frequently asked questions
What drug class is fenofibrate?
fenofibrate belongs to: Cardiovascular.
How does fenofibrate work?
Fenofibrate is a prodrug that is metabolized to the active moiety, fenofibric acid Activates peroxisome proliferator activated receptor-alpha (PPAR-alpha); increases lipolysis and elimination of triglyceride-rich particles from plasma by activating lipoprotein lipase and reduces Apo CIII production (lipoprotein lipase inhibitor)
What are the common side effects of fenofibrate?
Back pain, Increased LFT's, Respiratory disorder, Abdominal pain
Which drugs interact with fenofibrate?
valproic acid
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.