Drug reference
pilocarpine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Miscellaneous (Eye Preparations)
Mechanism of action
Cholinergic muscarinic agonist which activates muscarinic receptors located at smooth muscles (eg, iris sphincter muscle, ciliary muscle)
Contracts the ciliary muscle, causing increased tension on scleral spur and opening of trabecular meshwork spaces to facilitate outflow of aqueous humor; outflow resistance is reduced, lowering intraocular pressure (IOP).
Common side effects
- Headache
- Blurred vision
- Eye irritation
- Eye pain
Contraindications
- Hypersensitivity to drug or component.
Frequently asked questions
What drug class is pilocarpine?
pilocarpine belongs to: Miscellaneous.
How does pilocarpine work?
Cholinergic muscarinic agonist which activates muscarinic receptors located at smooth muscles (eg, iris sphincter muscle, ciliary muscle) Contracts the ciliary muscle, causing increased tension on scleral spur and opening of trabecular meshwork spaces to facilitate outflow of aqueous humor; outflow resistance is reduced, lowering intraocular pressure (IOP).
What are the common side effects of pilocarpine?
Headache, Blurred vision, Eye irritation, Eye pain
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