Drug reference
zafirlukast
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Respiratory (Leukotrienes Antagonist)
Mechanism of action
Inhibits bronchoconstriction as competitive receptor antagonist of leukotrienes D4 & E4; receptor occupation and cysteinyl leukotriene production has been associated with the pathophysiology of ashtma.
Common side effects
- Headache
- Nausea
- Infection
Contraindications
- Hypersensitivity Hepatic impairment, including cirrhosis; Cmax and AUC ~50-60% greater than those of normal adults
Related conditions
Frequently asked questions
What drug class is zafirlukast?
zafirlukast belongs to: Respiratory.
How does zafirlukast work?
Inhibits bronchoconstriction as competitive receptor antagonist of leukotrienes D4 & E4; receptor occupation and cysteinyl leukotriene production has been associated with the pathophysiology of ashtma.
What are the common side effects of zafirlukast?
Headache, Nausea, Infection
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